• Machine learning derived input-function in a dynamic 18F-FDG PET study of mice 

      Kuttner, Samuel; Wickstrøm, Kristoffer Knutsen; Kalda, Gustav; Dorraji, Seyed Esmaeil; Martin-Armas, Montserrat; Oteiza, Ana; Jenssen, Robert; Fenton, Kristin Andreassen; Sundset, Rune; Axelsson, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      Tracer kinetic modelling, based on dynamic <sup>18</sup>F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is used to quantify glucose metabolism in humans and animals. Knowledge of the arterial input-function (AIF) is required for such measurements. Our aim was to explore two non-invasive machine learning-based models, for AIF prediction in a small-animal dynamic FDG PET study. 7 tissue ...
    • Positron emission tomography and single photon emission computed tomography imaging of tertiary lymphoid structures during the development of lupus nephritis 

      Dorraji, Seyed Esmaeil; Oteiza, Ana; Kuttner, Samuel; Martin, Armas Maria Montserrat; Kanapathippillai, Premasany; Garbarino, Sara; Kalda, Gustav; Scussolini, Mara; Piana, Michele; Fenton, Kristin Andreassen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-03)
      Lymphoid neogenesis occurs in tissues targeted by chronic inflammatory processes, such as infection and autoimmunity. In systemic lupus erythematosus (SLE), such structures develop within the kidneys of lupus-prone mice ((NZBXNZW)F1) and are observed in kidney biopsies taken from SLE patients with lupus nephritis (LN). The purpose of this prospective longitudinal animal study was to detect early ...